Is cystatin C a marker of glomerular filtration rate in thyroid dysfunction?

نویسندگان

  • Jan G den Hollander
  • Raymond W Wulkan
  • Mart J Mantel
  • Arie Berghout
چکیده

[Letter]. Lancet 1998;352:959–60. 3. Madsen HO, Garred P, Thiel S, Kurtzhals J, Lamm LU, Ryder LP, et al A. Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein. J Immunol 1995;155:3013–20. 4. Madsen HO, Satz ML, Hogh B, Svejgaard A, Garred P. Different molecular events result in low protein levels of mannan-binding lectin in populations from southeast Africa and south America. J Immunol 1998;161:3169–75. 5. Turner MW, Dinan L, Heatley S, Jack DL, Boettcher B, Lester S, et al. Restricted polymorphism of the mannose-binding lectin gene of indigenous Australians. Hum Mol Genet 2000;9: 1481–6.

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Cystatin C: unsuited to use as a marker of kidney function in the intensive care unit

: We read with interest the article by Villa and coworkers 1 advocating the use of cystatin C as a measure of glomerular filtration rate (GFR) in critically ill patients. However, we should like to draw attention to several flaws in this study. First, Villa and coworkers compared cystatin C with creatinine as a measure of GFR, using body surface corrected creatinine clearance as, what they call...

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بررسی مقایسه‌ای ارزش تشخیصی سیستاتین C و کراتینین سرمی در ارزیابی عملکرد کلیه پیوندی در بیماران گیرنده کلیه در دوران اولیه پس از پیوند

   Background &Aim: Early detection of decreasing glomerular filtration rate (GFR) is critical to prevent graft rejection in post-transplantation period. Serum creatinine has several drawbacks as a marker of GFR, so serum cystatin C has been proposed as an alternative GFR marker. Thus, we prospectively evaluated the diagnostic value of cystatin C measurements compared with serum creatinine in t...

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عنوان ژورنال:
  • Clinical chemistry

دوره 49 9  شماره 

صفحات  -

تاریخ انتشار 2003